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1.
Engineered Cytochrome P450-Catalyzed Oxidative Biaryl Coupling Reaction Provides a Scalable Entry into Arylomycin Antibiotics.
J Am Chem Soc
; 144(32): 14838-14845, 2022 08 17.
Article
in English
| MEDLINE | ID: mdl-35905381
2.
Synthesis of a CGRP Receptor Antagonist via an Asymmetric Synthesis of 3-Fluoro-4-aminopiperidine.
J Org Chem
; 84(12): 8006-8018, 2019 06 21.
Article
in English
| MEDLINE | ID: mdl-31124362
3.
Catalytic, asymmetric, and stereodivergent synthesis of non-symmetric ß,ß-diaryl-α-amino acids.
J Am Chem Soc
; 137(2): 999-1006, 2015 Jan 21.
Article
in English
| MEDLINE | ID: mdl-25523503
4.
Palladium-catalyzed synthesis of 2-(aminomethyl)indoles from 3-(o-trifluoroacetamidoaryl)-1-propargylic alcohols and amines.
J Org Chem
; 79(1): 401-7, 2014 Jan 03.
Article
in English
| MEDLINE | ID: mdl-24308283
5.
Reaction of nitrosonium cation with resorc[4]arenes activated by supramolecular control: covalent bond formation.
J Org Chem
; 78(14): 6935-46, 2013 Jul 19.
Article
in English
| MEDLINE | ID: mdl-23786237
6.
Asymmetric Synthesis of N-Alkyl Amino Acids through a Biocatalytic Dynamic Kinetic Resolution of PEGylated N-Alkyl Amino Esters.
Org Lett
; 25(49): 8927-8931, 2023 12 15.
Article
in English
| MEDLINE | ID: mdl-38051775
7.
Introducing enantioselective ultrahigh-pressure liquid chromatography (eUHPLC): theoretical inspections and ultrafast separations on a new sub-2-µm Whelk-O1 stationary phase.
Anal Chem
; 84(15): 6805-13, 2012 Aug 07.
Article
in English
| MEDLINE | ID: mdl-22725676
8.
CRTH2 antagonist MK-7246: a synthetic evolution from discovery through development.
J Org Chem
; 77(5): 2299-309, 2012 Mar 02.
Article
in English
| MEDLINE | ID: mdl-22335767
9.
Preparative scale synthesis of the biaryl core of anacetrapib via a ruthenium-catalyzed direct arylation reaction: unexpected effect of solvent impurity on the arylation reaction.
J Org Chem
; 76(5): 1436-9, 2011 Mar 04.
Article
in English
| MEDLINE | ID: mdl-21284400
10.
A practical synthesis of renin inhibitor MK-1597 (ACT-178882) via catalytic enantioselective hydrogenation and epimerization of piperidine intermediate.
J Org Chem
; 76(4): 1062-71, 2011 Feb 18.
Article
in English
| MEDLINE | ID: mdl-21250716
11.
Azaindoles as potent CRTH2 receptor antagonists.
Bioorg Med Chem Lett
; 21(2): 841-5, 2011 Jan 15.
Article
in English
| MEDLINE | ID: mdl-21185722
12.
New indole amide derivatives as potent CRTH2 receptor antagonists.
Bioorg Med Chem Lett
; 21(11): 3471-4, 2011 Jun 01.
Article
in English
| MEDLINE | ID: mdl-21515053
13.
Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases.
Bioorg Med Chem Lett
; 21(1): 288-93, 2011 Jan 01.
Article
in English
| MEDLINE | ID: mdl-21106375
14.
A practical synthesis of 5-lipoxygenase inhibitor MK-0633.
J Org Chem
; 75(12): 4154-60, 2010 Jun 18.
Article
in English
| MEDLINE | ID: mdl-20486715
15.
Hybrid polyacrylamide chiral stationary phases for HPLC prepared by surface-initiated photopolymerization.
J Sep Sci
; 33(19): 3022-32, 2010 Oct.
Article
in English
| MEDLINE | ID: mdl-21038459
16.
Remote electronic control in the regioselective reduction of succinimides: a practical, scalable synthesis of Ep4 antagonist MF-310.
J Org Chem
; 74(17): 6863-6, 2009 Sep 04.
Article
in English
| MEDLINE | ID: mdl-19663395
17.
Stereocontrolled Synthesis of Arylomycin-Based Gram-Negative Antibiotic GDC-5338.
Org Lett
; 21(22): 9099-9103, 2019 11 15.
Article
in English
| MEDLINE | ID: mdl-31668077
18.
Synthesis of Verubecestat, a BACE1 Inhibitor for the Treatment of Alzheimer's Disease.
Org Lett
; 18(22): 5780-5783, 2016 11 18.
Article
in English
| MEDLINE | ID: mdl-27934506
19.
Discovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding Group.
ACS Med Chem Lett
; 7(7): 702-7, 2016 Jul 14.
Article
in English
| MEDLINE | ID: mdl-27437081
20.
Resolution of 2,2-disubstituted epoxides via biocatalytic azidolysis.
Org Lett
; 12(17): 3772-5, 2010 Sep 03.
Article
in English
| MEDLINE | ID: mdl-20681610